Price : Rs.295.00Rs.236.00 ISBN : 9788120342996
Page : 312 Year of Publication : 2011
Edition : Publisher : MIT Press
Description :
The Genetics of Cognitive Neuroscience aims to give the reader a working understanding of the influence of specific genetics variants on cognition, affective regulation, personality, and central nervous system disorders.
It has been known that the aspects of behavior runs in families; studies shows that characteristics related to cognition, temperament, and all major psychiatric disorders are heritable.
The book offers a primer on understanding the genetic mechanisms of such inherited traits.
The chapters emphasize fundamental issues regarding the design of experiments, the use of bioinformatics tools, the integration of data from different levels of analysis and the validity of finding, arguing that association between genes and cognitive processes must be replicable and placed in a neurobiological context for validation.
Content :
Preface Introduction I. Methodologies for Genetic Association Studies of Cognition
1 Molecular Genetics and Bioinformatics: An Outline for Neuropsychological Genetics—Lucas Kempf and Daniel R. Weinberger
2 Statistical Methods in Neuropsychiatric Genetics—Kristin K. Nicodemus and Fengyu Zhang
3 Animal Models of Genetic Effects on Cognition—Francesco Papaleo, Daniel R. Weinberger, and Jingshan Chen II Genetic Approaches to Individual Differences in Cognition and Affective Regulation
4 The Genetics of Intelligence Danielle Posthuma—Eco J.C. de Geus, and Ian J- Deary
5 Candidate Genes Associated with Attention and Cognitive Control—John Fossella, Jin Fan, and Michael I. Posner
6 Genetics of Corticolimbic Function and Emotional Reactivity—Ahmad R. Hariri, Erika E. Forbes, and Kristin L. Bigos
7 Genes Associated with Individual Differences in Cognitive Aging—Terry E. Goldberg and Venkata S. Mattay III Genetic Studies of Cognition and Treatment Response in Neuropsychiatric Disease
8 Genetics of Dyslexia: Cognitive Analysis, Candidate Genes, Comorbidities, and Etiologic Interactions—Bruce F. Pennington,
Lauren M. McGrath, and Shelley D. Smith
9 Cognitive Intermediate Phenotypes in Schizophrenia Genetics—Gary Donohoe, Terry E. Goldberg, and Aiden Corvin
10 The Genetic Basis for the Cognitive Deterioration of Alzheimer’s Disease—John M. Ringman and Jeffrey L. Cummings
11 Pharmacogenetic Approaches to Neurocognition in Schizophrenia—Katherine E. Burdick and Anil K. Malhotra Contributors Index